The 2025 Angels for Change Impact Report: 5 Years of Change Edition is here. This special mile5tone edition reflects on the progress, partnerships, and patient-centered solutions that shaped our journey and defined our impact in 2025.
Advocacy Alert: Angels for Change joins Industry Leaders in Official Comment Letters to CMS
Drug shortages affect real patients every single day—making reliable access to medication not just a goal, but a necessity. That’s why we’re proud to champion the patient voice in three important CMS comment letters focused on strengthening a more dependable and resilient drug supply.
At Angels for Change, advocacy is more than a mission—it’s action. By collaborating with leading partners such as the Duke-Margolis Institute for Health Policy, the End Drug Shortages Alliance (EDSA), and the U.S. Pharmacopeia Drug Shortage Task Force, we’re helping drive solutions that are both practical and firmly rooted in the real needs of patients.
Change Maker Chronicle: The March Forth Edition
Project PROTECT Milestone: U.S. Supply of Sterile Water for Injection Protected
Angels for Change is proud to announce a major Project PROTECT milestone: our partner Fagron Sterile Services is now fully production-ready with new U.S. capacity for Sterile Water for Injection—a critical component used in countless injectable medicines.
This marks the second successful Project PROTECT collaboration with Fagron, following earlier investments that helped protect patients during the IV fluid shortage in 2024. By investing in domestic manufacturing infrastructure, we’re strengthening the resilience of the U.S. drug supply and protecting patients before shortages occur.
We don’t just talk about ending drug shortages—we’re creating solutions that build onshore readiness, strengthen supply chains, and protect patient access to lifesaving medicines.
Project PROTECT Milestone: Angels for Change and Mark Cuban Cost Plus Drug Company have Strengthened the U.S. Supply of Carboplatin & Methotrexate
Angels for Change today announced that the Mark Cuban Cost Plus Drug Company has completed the Preparation and Protective phases of Project PROTECT for Carboplatin Injection and Methotrexate Injection—two essential oncology medicines currently in nationwide shortage. This milestone strengthens onshore readiness and improves supply availability for patients across the United States.
Angels for Change Convenes First Ever SummitONE PolicyLAB to Drive Action on the U.S. Drug Shortage Crisis
New from Angels for Change: the launch of our Policy Lab.
The A4C Policy Lab brings together patients, clinicians, policymakers, and industry leaders to turn frontline experience into actionable policy solutions that address drug shortages at their root.
Last week on January 29th, 2026, Angels for Change convened a sold-out National Policy Lab on Capitol Hill in the historic Kennedy Caucus Room to tackle one of the most urgent issues in healthcare: the U.S. drug shortage crisis.
Angels for Change is translating patient harm into real-world policy solutions. This Policy Lab wasn’t a conference — it was a working session focused on collaboration, candor, and outcomes, with patients at the center of every solution.
2025 Year in Review
Angels for Change — 2025 Year in Review
From supporting patients through dozens of different shortage crisis to launching a first-of-its-kind oncology resiliency program to shaping national policy conversations, 2025 was a year of bold action and patient-driven progress.
Together with partners across healthcare, government, and industry, we:
Protected patients during critical drug shortages
Launched Project GOLD to proactively safeguard cancer care
Protected 4 addition essential medicines for the American people with Project PROTECT
Elevated patient voices in policy and supply chain reform
Built momentum toward a more resilient medicine supply system
See how collaboration, transparency, and patient leadership are driving lasting change.
Change Maker Chronicle: Issue 14, Quarter 4, 2025
Project PROTECT Milestone to Strengthen U.S. Supply of Magnesium Sulfate
Angels for Change’s Project PROTECT has taken a significant step to strengthen preparedness for a lifesaving medicine, magnesium sulfate. In partnership with STAQ Pharma, magnesium sulfate is now ready for on-demand production, reinforcing resilience for a medicine essential to protecting mothers and newborns during emergencies and supply strain. This proactive readiness ensures patients receive vital treatment without delay.
A4C Awards 2025 Change Maker of the Year
Angels for Change Honors 2025 Change Maker of the Year
Angels for Change has named Vimala Raghavendran, Vice President at the U.S. Pharmacopeia (USP), as the 2025 Change Maker of the Year. Raghavendran created the groundbreaking Medicine Supply Map, a first-of-its-kind tool used nationwide to uncover vulnerabilities in the medicine supply chain and prevent drug shortages.
Her innovation has powered lifesaving work at A4C and beyond — strengthening access to critical medicines and protecting patients.
