Angels for Change and Medivant Healthcare Advance U.S. Readiness for Critical Calcium Chloride Injection

Angels for Change and Medivant Healthcare Advance U.S. Readiness for Critical Calcium Chloride Injection

Announcing: A new milestone to strengthen U.S. readiness for critical medicines.

Today, Angels for Change and Medivant Healthcare announced the completion of a key Project PROTECT milestone, establishing ready-to-activate U.S. manufacturing capacity for 10% Calcium Chloride Injection, an essential medicine used in emergency and critical care.

Through the partnership, Medivant has completed development of Calcium Chloride Injection and advanced the medicine into Project PROTECT’s readiness phase, creating domestic manufacturing capacity that can be activated when supply disruptions threaten patient access.

“Project PROTECT is about staying ahead of shortages before they reach patients,” said Laura Bray, Chief Change Maker at Angels for Change. “By partnering with Medivant Healthcare to prepare domestic capacity for Calcium Chloride Injection, we are demonstrating what proactive shortage preparedness can look like and building the ability to respond before a supply disruption becomes a patient crisis.”

Since launching in 2022, Project PROTECT has strengthened U.S. readiness for 14 essential medicines, seven of which have subsequently experienced shortages, with more than 850,000 patient treatments accessed during shortages.

Patient One, Now a Patient Advocate: Abby Bray Shares Her Story

Patient One, Now a Patient Advocate: Abby Bray Shares Her Story

For the first time since 2019, Abby Bray is sharing her cancer journey in her own words.

For years, Abby kept her story private. Now, five years cancer-free, she is choosing to share her experience and use her voice to advocate for other patients facing drug shortages.

Abby was Patient One for Angels for Change.

Today, she is helping carry that mission forward as a member of the Angels for Change Patient Advocacy Board, which brings patients, caregivers, and lived experiences directly into our advocacy work.

Angels for Change Brings Pharmaceutical Leaders Together at SummitONE 2026 to Advance a More Resilient Drug Supply Chain

Angels for Change Brings Pharmaceutical Leaders Together at SummitONE 2026 to Advance a More Resilient Drug Supply Chain

Angels for Change (A4C) successfully concluded its sold out SummitONE 2026, its annual healthcare summit focused on strengthening pharmaceutical supply chain resilience, at Pfizer's headquarters in New York City. The two-day event brought together executives and experts from across the pharmaceutical ecosystem; including manufacturers, distributors, healthcare systems, regulators, policymakers, and patient advocates. SummitONE advances collaboration and actionable solutions to strengthen access to medicines and end drug shortages.

Angels for Change Launches Project GOLD Phase 2

Angels for Change Launches Project GOLD Phase 2

Project GOLD is growing. Building on the success of its groundbreaking first phase, Angels for Change has launched Project GOLD Phase 2, expanding the nation's first collaborative initiative designed to protect cancer patients from drug shortages. With new manufacturer and distributor partners and an expanded portfolio of 15 high-risk oncology medicines, Phase 2 strengthens a proven model built on strategic U.S.-based buffer supply, early warning systems, and cross-sector collaboration. Following the successful protection of patient access during the national leucovorin shortage, Project GOLD continues to demonstrate that when industry leaders unite around a shared commitment to patients, together we can build a more resilient pharmaceutical supply chain and help ensure lifesaving cancer treatments remain available when patients need them most.

Angels for Change Releases New White Paper Highlighting Project GOLD as a National Model for Protecting Cancer Patients During Drug Shortages

Angels for Change Releases New White Paper Highlighting Project GOLD as a National Model for Protecting Cancer Patients During Drug Shortages

Angels for Change, through its Change Makers Institute, today announced the release of a new white paper, How Buffer Stock, Proactive Coordination, and Patient Advocacy Have Become a National Lifeline for Cancer Patients, highlighting the development and success of Project GOLD (Generic Oncology Lifesaving Drugs).

Angels for Change and Every Cure Announce Collaboration to Advance Patient Access to Repurposed Medicines

Angels for Change and Every Cure Announce Collaboration to Advance Patient Access to Repurposed Medicines

Angels for Change and Every Cure announced a collaboration aimed at strengthening patient access to repurposed medicines and advancing a more resilient, patient-centered healthcare system.

Angels for Change and Every Cure share a commitment to ensuring patients have access to the treatments they need– whether that means discovering and advancing new uses for existing medicines or ensuring those medicines are available when patients need them. By combining expertise in drug shortages, supply chain resilience, and drug repurposing, the partnership will support shared efforts to expand access to lifesaving therapies. Particularly for generic essential medicines that form the backbone of healthcare. 

USP 2025 Annual Drug Shortage Report

USP 2025 Annual Drug Shortage Report

The 2025 USP Drug Shortages Report has been released, and it highlights a troubling trend: discontinuations of essential, life-saving medicines continue to rise.

In 2025, drug product discontinuations increased by 60%, reaching the highest annual total in 5 years. Drug shortages are often driven by single points of failure; medicines that are manufactured at only one facility or place in the world. When products are discontinued, the market becomes even more concentrated, leaving patients with fewer treatment options and fewer backup sources when disruptions occur.