The newest Change Maker Chronicle is here! Drug shortages are still impacting patients every day, but together we are pushing forward. See how we’re raising awareness, fostering advocacy, and building resilent drug supply chains to end drug shortages NOW.
Angels for Change Releases New White Paper Highlighting Project GOLD as a National Model for Protecting Cancer Patients During Drug Shortages
Angels for Change, through its Change Makers Institute, today announced the release of a new white paper, How Buffer Stock, Proactive Coordination, and Patient Advocacy Have Become a National Lifeline for Cancer Patients, highlighting the development and success of Project GOLD (Generic Oncology Lifesaving Drugs).
Laura Bray Quoted in The New York Times Article on Chemotherapy Drug Shortage Concerns
Angels for Change and Every Cure Announce Collaboration to Advance Patient Access to Repurposed Medicines
Angels for Change and Every Cure announced a collaboration aimed at strengthening patient access to repurposed medicines and advancing a more resilient, patient-centered healthcare system.
Angels for Change and Every Cure share a commitment to ensuring patients have access to the treatments they need– whether that means discovering and advancing new uses for existing medicines or ensuring those medicines are available when patients need them. By combining expertise in drug shortages, supply chain resilience, and drug repurposing, the partnership will support shared efforts to expand access to lifesaving therapies. Particularly for generic essential medicines that form the backbone of healthcare.
USP 2025 Annual Drug Shortage Report
The 2025 USP Drug Shortages Report has been released, and it highlights a troubling trend: discontinuations of essential, life-saving medicines continue to rise.
In 2025, drug product discontinuations increased by 60%, reaching the highest annual total in 5 years. Drug shortages are often driven by single points of failure; medicines that are manufactured at only one facility or place in the world. When products are discontinued, the market becomes even more concentrated, leaving patients with fewer treatment options and fewer backup sources when disruptions occur.
2025 Annual Report
Project PROTECT Milestone: Angels for Change and Medivant Healthcare Expand U.S. Supply of Critical Calcium Chloride Injection
Angels for Change announced a major milestone in Project PROTECT, its national initiative focused on building ready-to-activate domestic manufacturing capacity for essential medicines vulnerable to shortages. Through a new partnership with Medivant Healthcare, 10% Calcium Chloride Injection is now protected with onshore manufacturing readiness in the U.S., helping safeguard patient access during future supply disruptions. The collaboration strengthens domestic supply chain resilience for this critical medication used in emergency medicine, cardiac resuscitation, and intensive care.
What the Iran war could mean for pharmaceuticals
Angels for Change Joins USP Convention
At Angels for Change, we believe that ending drug shortages requires more than urgency, it requires alignment, collaboration, and bold action across every part of the healthcare ecosystem.
That’s why we’re extremely proud to be recognized by the U.S. Pharmacopeia Convention as a voting member among a diverse network of more than 450 organizations working together to strengthen trust in medicines and improve global health outcomes.
Spotlight on America: Cancer drug shortages leave families waiting; Texas startup tries to fill the gap
This Spotlight on America report follows families like Bryton’s, whose cancer treatment was overshadowed by the fear of drug shortages—forcing them to wait and wonder if life-saving medications would be available. As shortages of essential chemotherapy drugs disrupt care nationwide, the story highlights both the human toll of an unstable supply chain and emerging solutions.



