Press Release, A4C News
Laura Bray
Project PROTECT Milestone: Angels for Change ...

Angels for Change announced a major milestone in Project PROTECT, its national initiative focused on building ready-to-activate domestic manufacturing capacity for essential medicines vulnerable to shortages. Through the partnership, Leiters Health, a U.S.-based 503B outsourcing facility in Englewood, Colorado, has completed development of Magnesium Sulfate Injection and advanced the medicine into PROTECT's readiness phase. The partnership establishes domestic manufacturing capacity that can be activated when supply disruptions threaten access to this critical medication.

Project PROTECT Milestone: Angels for Change and Leiters Health Advance U.S. Readiness for Critical Medicine Magnesium Sulfate Injection 
A4C News, Newsletter
Rachel Splinter
Change Maker Chronicle: Q3 2026 Edition

The newest Change Maker Chronicle is here! Drug shortages are still impacting patients every day, but together we are pushing forward. See how we’re raising awareness, fostering advocacy, and building resilent drug supply chains to end drug shortages NOW.

Change Maker Chronicle: Q3 2026 Edition
In the News
Rachel Splinter
Cancer drug shortages threaten lives as efforts ...

Drug shortages continue to put patients at risk.

As highlighted by The National Desk’s Spotlight on America, children with cancer and their families continue to face uncertainty when critical medicines like ifosfamide are in short supply.

For Abby Bray, this was personal. Patient One was Abby. Her experience navigating drug shortages during cancer treatment became the catalyst for Laura Bray’s advocacy and the founding of Angels for Change.

We remain committed to advancing solutions that strengthen the pharmaceutical supply chain and ensure every patient has access to the medicines they need.

Cancer drug shortages threaten lives as efforts to prevent them hit regulatory red tape
In the News
Rachel Splinter
Laura Bray featured in the New York Post Amid ...

Women across the country are struggling to access estrogen patches, with some traveling long distances, rationing medication, or searching for alternatives to maintain access to their treatment.

The New York Post recently examined the shortage and the challenges patients are facing. Laura Bray, Founder of Angels for Change, spoke with the publication about why the shortage was predictable following the FDA’s removal of the black box warning for estrogen-based hormone replacement therapy.

Laura Bray featured in the New York Post Amid Estrogen Patch Shortage
Press Release
Rachel Splinter
Angels for Change and Medivant Healthcare ...

Announcing: A new milestone to strengthen U.S. readiness for critical medicines.

Today, Angels for Change and Medivant Healthcare announced the completion of a key Project PROTECT milestone, establishing ready-to-activate U.S. manufacturing capacity for 10% Calcium Chloride Injection, an essential medicine used in emergency and critical care.

Through the partnership, Medivant has completed development of Calcium Chloride Injection and advanced the medicine into Project PROTECT’s readiness phase, creating domestic manufacturing capacity that can be activated when supply disruptions threaten patient access.

“Project PROTECT is about staying ahead of shortages before they reach patients,” said Laura Bray, Chief Change Maker at Angels for Change. “By partnering with Medivant Healthcare to prepare domestic capacity for Calcium Chloride Injection, we are demonstrating what proactive shortage preparedness can look like and building the ability to respond before a supply disruption becomes a patient crisis.”

Since launching in 2022, Project PROTECT has strengthened U.S. readiness for 14 essential medicines, seven of which have subsequently experienced shortages, with more than 850,000 patient treatments accessed during shortages.

Angels for Change and Medivant Healthcare Advance U.S. Readiness for Critical Calcium Chloride Injection

A4C News

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Project PROTECT Milestone: Angels for Change and Leiters Health Advance U.S. Readiness for Critical Medicine Magnesium Sulfate Injection 

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Project PROTECT Milestone: Angels for Change and Leiters Health Advance U.S. Readiness for Critical Medicine Magnesium Sulfate Injection 

Angels for Change announced a major milestone in Project PROTECT, its national initiative focused on building ready-to-activate domestic manufacturing capacity for essential medicines vulnerable to shortages. Through the partnership, Leiters Health, a U.S.-based 503B outsourcing facility in Englewood, Colorado, has completed development of Magnesium Sulfate Injection and advanced the medicine into PROTECT's readiness phase. The partnership establishes domestic manufacturing capacity that can be activated when supply disruptions threaten access to this critical medication.

Advocacy Alert: Angels for Change joins Industry Leaders in Official Comment Letters to CMS

Advocacy Alert: Angels for Change joins Industry Leaders in Official Comment Letters to CMS

Drug shortages affect real patients every single day—making reliable access to medication not just a goal, but a necessity. That’s why we’re proud to champion the patient voice in three important CMS comment letters focused on strengthening a more dependable and resilient drug supply.

At Angels for Change, advocacy is more than a mission—it’s action. By collaborating with leading partners such as the Duke-Margolis Institute for Health Policy, the End Drug Shortages Alliance (EDSA), and the U.S. Pharmacopeia Drug Shortage Task Force, we’re helping drive solutions that are both practical and firmly rooted in the real needs of patients.

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Project PROTECT Milestone: U.S. Supply of Sterile Water for Injection Protected

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Project PROTECT Milestone: U.S. Supply of Sterile Water for Injection Protected

Angels for Change is proud to announce a major Project PROTECT milestone: our partner Fagron Sterile Services is now fully production-ready with new U.S. capacity for Sterile Water for Injection—a critical component used in countless injectable medicines.

This marks the second successful Project PROTECT collaboration with Fagron, following earlier investments that helped protect patients during the IV fluid shortage in 2024. By investing in domestic manufacturing infrastructure, we’re strengthening the resilience of the U.S. drug supply and protecting patients before shortages occur.

We don’t just talk about ending drug shortages—we’re creating solutions that build onshore readiness, strengthen supply chains, and protect patient access to lifesaving medicines.

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Project PROTECT Milestone: Angels for Change and Mark Cuban Cost Plus Drug Company have Strengthened the U.S. Supply of Carboplatin & Methotrexate

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Project PROTECT Milestone: Angels for Change and Mark Cuban Cost Plus Drug Company have Strengthened the U.S. Supply of Carboplatin & Methotrexate

Angels for Change today announced that the Mark Cuban Cost Plus Drug Company has completed the Preparation and Protective phases of Project PROTECT for Carboplatin Injection and Methotrexate Injection—two essential oncology medicines currently in nationwide shortage. This milestone strengthens onshore readiness and improves supply availability for patients across the United States.

Angels for Change Convenes First Ever SummitONE PolicyLAB to Drive Action on the U.S. Drug Shortage Crisis

Angels for Change Convenes First Ever SummitONE PolicyLAB to Drive Action on the U.S. Drug Shortage Crisis

New from Angels for Change: the launch of our Policy Lab.

The A4C Policy Lab brings together patients, clinicians, policymakers, and industry leaders to turn frontline experience into actionable policy solutions that address drug shortages at their root.

Last week on January 29th, 2026, Angels for Change convened a sold-out National Policy Lab on Capitol Hill in the historic Kennedy Caucus Room to tackle one of the most urgent issues in healthcare: the U.S. drug shortage crisis.

Angels for Change is translating patient harm into real-world policy solutions. This Policy Lab wasn’t a conference — it was a working session focused on collaboration, candor, and outcomes, with patients at the center of every solution.

2025 Year in Review

2025 Year in Review

Angels for Change — 2025 Year in Review

From supporting patients through dozens of different shortage crisis to launching a first-of-its-kind oncology resiliency program to shaping national policy conversations, 2025 was a year of bold action and patient-driven progress.

Together with partners across healthcare, government, and industry, we:

  • Protected patients during critical drug shortages

  • Launched Project GOLD to proactively safeguard cancer care

  • Protected 4 addition essential medicines for the American people with Project PROTECT 

  • Elevated patient voices in policy and supply chain reform

  • Built momentum toward a more resilient medicine supply system

See how collaboration, transparency, and patient leadership are driving lasting change.

SHARE YOUR “WHY”

Every conversation, partnership, and shared story brings us closer to a future without drug shortages. At Angels for Change, we’re proud to march forth for patients everywhere.

SHARE YOUR STORY