Angels for Change (A4C) successfully concluded its sold out SummitONE 2026, its annual healthcare summit focused on strengthening pharmaceutical supply chain resilience, at Pfizer's headquarters in New York City. The two-day event brought together executives and experts from across the pharmaceutical ecosystem; including manufacturers, distributors, healthcare systems, regulators, policymakers, and patient advocates. SummitONE advances collaboration and actionable solutions to strengthen access to medicines and end drug shortages.
Project GOLD is growing. Building on the success of its groundbreaking first phase, Angels for Change has launched Project GOLD Phase 2, expanding the nation's first collaborative initiative designed to protect cancer patients from drug shortages. With new manufacturer and distributor partners and an expanded portfolio of 15 high-risk oncology medicines, Phase 2 strengthens a proven model built on strategic U.S.-based buffer supply, early warning systems, and cross-sector collaboration. Following the successful protection of patient access during the national leucovorin shortage, Project GOLD continues to demonstrate that when industry leaders unite around a shared commitment to patients, together we can build a more resilient pharmaceutical supply chain and help ensure lifesaving cancer treatments remain available when patients need them most.
The newest Change Maker Chronicle is here! Drug shortages are still impacting patients every day, but together we are pushing forward. See how we’re raising awareness, fostering advocacy, and building resilent drug supply chains to end drug shortages NOW.
Angels for Change, through its Change Makers Institute, today announced the release of a new white paper, How Buffer Stock, Proactive Coordination, and Patient Advocacy Have Become a National Lifeline for Cancer Patients, highlighting the development and success of Project GOLD (Generic Oncology Lifesaving Drugs).
At Angels for Change, we believe that ending drug shortages requires more than urgency, it requires alignment, collaboration, and bold action across every part of the healthcare ecosystem.
That’s why we’re extremely proud to be recognized by the U.S. Pharmacopeia Convention as a voting member among a diverse network of more than 450 organizations working together to strengthen trust in medicines and improve global health outcomes.
This Spotlight on America report follows families like Bryton’s, whose cancer treatment was overshadowed by the fear of drug shortages—forcing them to wait and wonder if life-saving medications would be available. As shortages of essential chemotherapy drugs disrupt care nationwide, the story highlights both the human toll of an unstable supply chain and emerging solutions.
Drug shortages affect real patients every single day—making reliable access to medication not just a goal, but a necessity. That’s why we’re proud to champion the patient voice in three important CMS comment letters focused on strengthening a more dependable and resilient drug supply.
At Angels for Change, advocacy is more than a mission—it’s action. By collaborating with leading partners such as the Duke-Margolis Institute for Health Policy, the End Drug Shortages Alliance (EDSA), and the U.S. Pharmacopeia Drug Shortage Task Force, we’re helping drive solutions that are both practical and firmly rooted in the real needs of patients.
Angels for Change is proud to announce a major Project PROTECT milestone: our partner Fagron Sterile Services is now fully production-ready with new U.S. capacity for Sterile Water for Injection—a critical component used in countless injectable medicines.
This marks the second successful Project PROTECT collaboration with Fagron, following earlier investments that helped protect patients during the IV fluid shortage in 2024. By investing in domestic manufacturing infrastructure, we’re strengthening the resilience of the U.S. drug supply and protecting patients before shortages occur.
We don’t just talk about ending drug shortages—we’re creating solutions that build onshore readiness, strengthen supply chains, and protect patient access to lifesaving medicines.
Laura Bray and Angels for Change highlighted in the newly released white paper from the API Innovation Center, “Fragility to Resilience: Aligning Investment and Purchasing to Secure America’s Drug Supply Chain.”
Bray emphasized a clear call to action for leaders across the healthcare ecosystem to work together to solve the drug shortage crisis:
“This is not the patient’s job to solve at all… This is a supply chain failure.”
Drug shortages are making national headlines again as families search for critical medicines like leucovorin. In a recent CNN article, Angels for Change founder Laura Bray highlights how the crisis was predictable—and preventable. Through Project GOLD, Angels for Change works across the supply chain to locate scarce medications and help patients access the treatments they depend on, because no family should have to face a shortage alone.
At Angels for Change, we are proud to participate in the important work of the End Drug Shortages Alliance — serving as both an EDSA member organization and advising partner in the Drug Resiliency & Transparency Pilot.
The initial phase of the pilot demonstrated a powerful truth: when leaders come together early through trusted, neutral governance, transparency delivers real planning value.
Angels for Change today announced that the Mark Cuban Cost Plus Drug Company has completed the Preparation and Protective phases of Project PROTECT for Carboplatin Injection and Methotrexate Injection—two essential oncology medicines currently in nationwide shortage. This milestone strengthens onshore readiness and improves supply availability for patients across the United States.
Drug shortages are not just a supply chain problem—they are personal. In this Capitol Hill briefing hosted by U.S. Pharmacopeia (USP), patients share firsthand how medication shortages have disrupted care, created fear and uncertainty, and put lives at risk. Their stories underscore the urgent need for stronger policies, better transparency, and a more resilient drug supply system—because patients are counting on us.
SHARE YOUR “WHY”
Every conversation, partnership, and shared story brings us closer to a future without drug shortages. At Angels for Change, we’re proud to march forth for patients everywhere.
