Press Release
Rachel Splinter
Angels for Change and Medivant Healthcare ...

Announcing: A new milestone to strengthen U.S. readiness for critical medicines.

Today, Angels for Change and Medivant Healthcare announced the completion of a key Project PROTECT milestone, establishing ready-to-activate U.S. manufacturing capacity for 10% Calcium Chloride Injection, an essential medicine used in emergency and critical care.

Through the partnership, Medivant has completed development of Calcium Chloride Injection and advanced the medicine into Project PROTECT’s readiness phase, creating domestic manufacturing capacity that can be activated when supply disruptions threaten patient access.

“Project PROTECT is about staying ahead of shortages before they reach patients,” said Laura Bray, Chief Change Maker at Angels for Change. “By partnering with Medivant Healthcare to prepare domestic capacity for Calcium Chloride Injection, we are demonstrating what proactive shortage preparedness can look like and building the ability to respond before a supply disruption becomes a patient crisis.”

Since launching in 2022, Project PROTECT has strengthened U.S. readiness for 14 essential medicines, seven of which have subsequently experienced shortages, with more than 850,000 patient treatments accessed during shortages.

Angels for Change and Medivant Healthcare Advance U.S. Readiness for Critical Calcium Chloride Injection
In the News
Rachel Splinter
Patient One, Now a Patient Advocate: Abby Bray ...

For the first time since 2019, Abby Bray is sharing her cancer journey in her own words.

For years, Abby kept her story private. Now, five years cancer-free, she is choosing to share her experience and use her voice to advocate for other patients facing drug shortages.

Abby was Patient One for Angels for Change.

Today, she is helping carry that mission forward as a member of the Angels for Change Patient Advocacy Board, which brings patients, caregivers, and lived experiences directly into our advocacy work.

Patient One, Now a Patient Advocate: Abby Bray Shares Her Story
Press Release
Rachel Splinter
Angels for Change Brings Pharmaceutical Leaders ...

Angels for Change (A4C) successfully concluded its sold out SummitONE 2026, its annual healthcare summit focused on strengthening pharmaceutical supply chain resilience, at Pfizer's headquarters in New York City. The two-day event brought together executives and experts from across the pharmaceutical ecosystem; including manufacturers, distributors, healthcare systems, regulators, policymakers, and patient advocates. SummitONE advances collaboration and actionable solutions to strengthen access to medicines and end drug shortages.

Angels for Change Brings Pharmaceutical Leaders Together at SummitONE 2026 to Advance a More Resilient Drug Supply Chain
Rachel Splinter
Angels for Change Launches Project GOLD Phase 2

Project GOLD is growing. Building on the success of its groundbreaking first phase, Angels for Change has launched Project GOLD Phase 2, expanding the nation's first collaborative initiative designed to protect cancer patients from drug shortages. With new manufacturer and distributor partners and an expanded portfolio of 15 high-risk oncology medicines, Phase 2 strengthens a proven model built on strategic U.S.-based buffer supply, early warning systems, and cross-sector collaboration. Following the successful protection of patient access during the national leucovorin shortage, Project GOLD continues to demonstrate that when industry leaders unite around a shared commitment to patients, together we can build a more resilient pharmaceutical supply chain and help ensure lifesaving cancer treatments remain available when patients need them most.

Angels for Change Launches Project GOLD Phase 2
A4C News, Newsletter
Rachel Splinter
Change Maker Chronicle: The March Forth Edition

The newest Change Maker Chronicle is here! Drug shortages are still impacting patients every day, but together we are pushing forward. See how we’re raising awareness, fostering advocacy, and building resilent drug supply chains to end drug shortages NOW.

Change Maker Chronicle: The March Forth Edition

Project PROTECT Milestone: Angels for Change and Medivant Healthcare Expand U.S. Supply of Critical Calcium Chloride Injection

Project PROTECT Milestone: Angels for Change and Medivant Healthcare Expand U.S. Supply of Critical Calcium Chloride Injection

Angels for Change announced a major milestone in Project PROTECT, its national initiative focused on building ready-to-activate domestic manufacturing capacity for essential medicines vulnerable to shortages. Through a new partnership with Medivant Healthcare, 10% Calcium Chloride Injection is now protected with onshore manufacturing readiness in the U.S., helping safeguard patient access during future supply disruptions. The collaboration strengthens domestic supply chain resilience for this critical medication used in emergency medicine, cardiac resuscitation, and intensive care.

Angels for Change Joins USP Convention

Angels for Change Joins USP Convention

At Angels for Change, we believe that ending drug shortages requires more than urgency, it requires alignment, collaboration, and bold action across every part of the healthcare ecosystem.

That’s why we’re extremely proud to be recognized by the U.S. Pharmacopeia Convention as a voting member among a diverse network of more than 450 organizations working together to strengthen trust in medicines and improve global health outcomes.

Spotlight on America: Cancer drug shortages leave families waiting; Texas startup tries to fill the gap

Spotlight on America: Cancer drug shortages leave families waiting; Texas startup tries to fill the gap

This Spotlight on America report follows families like Bryton’s, whose cancer treatment was overshadowed by the fear of drug shortages—forcing them to wait and wonder if life-saving medications would be available. As shortages of essential chemotherapy drugs disrupt care nationwide, the story highlights both the human toll of an unstable supply chain and emerging solutions.

Advocacy Alert: Angels for Change joins Industry Leaders in Official Comment Letters to CMS

Advocacy Alert: Angels for Change joins Industry Leaders in Official Comment Letters to CMS

Drug shortages affect real patients every single day—making reliable access to medication not just a goal, but a necessity. That’s why we’re proud to champion the patient voice in three important CMS comment letters focused on strengthening a more dependable and resilient drug supply.

At Angels for Change, advocacy is more than a mission—it’s action. By collaborating with leading partners such as the Duke-Margolis Institute for Health Policy, the End Drug Shortages Alliance (EDSA), and the U.S. Pharmacopeia Drug Shortage Task Force, we’re helping drive solutions that are both practical and firmly rooted in the real needs of patients.

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Project PROTECT Milestone: U.S. Supply of Sterile Water for Injection Protected

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Project PROTECT Milestone: U.S. Supply of Sterile Water for Injection Protected

Angels for Change is proud to announce a major Project PROTECT milestone: our partner Fagron Sterile Services is now fully production-ready with new U.S. capacity for Sterile Water for Injection—a critical component used in countless injectable medicines.

This marks the second successful Project PROTECT collaboration with Fagron, following earlier investments that helped protect patients during the IV fluid shortage in 2024. By investing in domestic manufacturing infrastructure, we’re strengthening the resilience of the U.S. drug supply and protecting patients before shortages occur.

We don’t just talk about ending drug shortages—we’re creating solutions that build onshore readiness, strengthen supply chains, and protect patient access to lifesaving medicines.

Laura Bray Featured in APIIC White Paper on Strengthening the Drug Supply Chain

Laura Bray Featured in APIIC White Paper on Strengthening the Drug Supply Chain

Laura Bray and Angels for Change highlighted in the newly released white paper from the API Innovation Center, “Fragility to Resilience: Aligning Investment and Purchasing to Secure America’s Drug Supply Chain.”

Bray emphasized a clear call to action for leaders across the healthcare ecosystem to work together to solve the drug shortage crisis:

“This is not the patient’s job to solve at all… This is a supply chain failure.”

Angels for Change and Project GOLD highlighted in CNN article about the current Leucovorin Drug Shortage in the U.S.

Angels for Change and Project GOLD highlighted in CNN article about the current Leucovorin Drug Shortage in the U.S.

Drug shortages are making national headlines again as families search for critical medicines like leucovorin. In a recent CNN article, Angels for Change founder Laura Bray highlights how the crisis was predictable—and preventable. Through Project GOLD, Angels for Change works across the supply chain to locate scarce medications and help patients access the treatments they depend on, because no family should have to face a shortage alone.

Angels for Change serves as Advising Member in the Drug Resiliency & Transparency Pilot

Angels for Change serves as Advising Member in the Drug Resiliency & Transparency Pilot

At Angels for Change, we are proud to participate in the important work of the End Drug Shortages Alliance — serving as both an EDSA member organization and advising partner in the Drug Resiliency & Transparency Pilot.

The initial phase of the pilot demonstrated a powerful truth: when leaders come together early through trusted, neutral governance, transparency delivers real planning value.

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Every conversation, partnership, and shared story brings us closer to a future without drug shortages. At Angels for Change, we’re proud to march forth for patients everywhere.

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